College of Agricultural Sciences

G. G. Sharma, Cortinovis, D., Agustoni, F., Arosio, G., Villa, M., Cordani, N., Bidoli, P., Bisson, W. H., Pagni, F., Piazza, R., Gambacorti-Passerini, C., and Mologni, L., “A Compound L1196M/G1202R ALK Mutation in a Patient with ALK-Positive Lung Cancer with Acquired Resistance to Brigatinib Also Confers Primary Resistance to Lorlatinib”, Journal of Thoracic Oncology, vol. 14, no. 11, pp. e257 - e259, 2019.

S. K. Joshi, Bisson, W. H., Qian, K., Huang, A., Watanabe-Smith, K., Tyner, J. W., Davare, M. Ashok, McWeeney, S. K., Tognon, C. E., and Druker, B. J., “Discovery & Characterization of Therapeutically Targetable Ntrk Point Mutations in LeukemiaDisclosures”, Blood, vol. 134, no. Supplement_1, pp. 1256 - 1256, 2019.

B. C. Brinchmann, Le Ferrec, E., Bisson, W. H., Podechard, N., Huitfeldt, H. S., Gallais, I., Sergent, O., Holme, ørnA., Lagadic-Gossmann, D., and Øvrevik, J., “Evidence of selective activation of aryl hydrocarbon receptor nongenomic calcium signaling by pyrene”, Biochemical Pharmacology, vol. 158, pp. 1 - 12, 2018.

L. Sun, Xie, C., Wang, G., Wu, Y., Wu, Q., Wang, X., Liu, J., Deng, Y., Xia, J., Chen, B., Zhang, S., Yun, C., Lian, G., Zhang, X., Zhang, H., Bisson, W. H., Shi, J., Gao, X., Ge, P., Liu, C., Krausz, K. W., Nichols, R. G., Cai, J., Rimal, B., Patterson, A. D., Wang, X., Gonzalez, F. J., and Jiang, C., “Gut microbiota and intestinal FXR mediate the clinical benefits of metformin.”, Nat Med, 2018.

A. Sehrawat, Gao, L., Wang, Y., Bankhead, A., McWeeney, S. K., King, C. J., Schwartzman, J., Urrutia, J., Bisson, W. H., Coleman, D. J., Joshi, S. K., Kim, D. - H., Sampson, D. A., Weinmann, S., Kallakury, B. V. S., Berry, D. L., Haque, R., Van Den Eeden, S. K., Sharma, S., Bearss, J., Beer, T. M., Thomas, G. V., Heiser, L. M., and Alumkal, J. J., “LSD1 activates a lethal prostate cancer gene network independently of its demethylase function.”, Proc Natl Acad Sci U S A, 2018.

Y. Zhang, Yan, T., Sun, D., Xie, C., Zheng, Y., Zhang, L., Yagai, T., Krausz, K. W., Bisson, W. H., Yang, X., and Gonzalez, F. J., “Structure-activity relationships of the main bioactive constituents of Euodia ruticarpa on aryl hydrocarbon receptor activation and bile acid homeostasis”, Drug Metabolism and Disposition, p. dmd.117.080176, 2018.

A. K. Ehrlich, Pennington, J. M., Bisson, W. H., Kolluri, S., and Kerkvliet, N. I., “TCDD, FICZ, and other high affinity AhR ligands dose-dependently determine the fate of CD4+ T cell differentiation.”, Toxicol Sci, 2018.

W. H. Bisson, Amedei, A., Memeo, L., Forte, S., and Felsher, D. W., “Tumor-Promoting/Associated Inflammation and the Microenvironment: A State of the Science and New Horizons”, Hoboken, NJ, USA: John Wiley & Sons, Inc., 2018, pp. 473 - 510.

L. R. Zarour, Anand, S., Billingsley, K. G., Bisson, W. H., Cercek, A., Clarke, M. F., Coussens, L. M., Gast, C. E., Geltzeiler, C. B., Hansen, L., Kelley, K. A., Lopez, C. D., Rana, S. R., Ruhl, R., V Tsikitis, L., Vaccaro, G. M., Wong, M. H., and Mayo, S. C., “Colorectal Cancer Liver Metastasis: Evolving Paradigms and Future Directions.”, Cell Mol Gastroenterol Hepatol, vol. 3, no. 2, pp. 163-173, 2017.

W. H. Bisson, “Environmental immune disruptors, inflammation and carcinogenesis: A state of the science and new horizons”, Toxicology Letters, vol. 280, pp. S9 - S10, 2017.

H. Sang Jang, Pearce, M. C., O'Donnell, E. F., Nguyen, B. Duc, Truong, L., Mueller, M. J., Bisson, W. H., Kerkvliet, N. I., Tanguay, R. L., and Kolluri, S., “Identification of a Raloxifene Analog That Promotes AhR-Mediated Apoptosis in Cancer Cells.”, Biology (Basel), vol. 6, no. 4, 2017.

H. Jang, Pearce, M. C., O'Donnell, E. F., Nguyen, B., Truong, L., Mueller, M. J., Bisson, W. H., Kerkvliet, N. I., Tanguay, R. L., and Kolluri, S., “Identification of a Raloxifene Analog That Promotes AhR-Mediated Apoptosis in Cancer Cells”, Biology (Basel), vol. 6, no. 4, 2017.

M. F. Miller, Goodson, W. H., Manjili, M. H., Kleinstreuer, N., Bisson, W. H., and Lowe, L., “Low-Dose Mixture Hypothesis of Carcinogenesis Workshop: Scientific Underpinnings and Research Recommendations.”, Environ Health Perspect, 2017.

A. C. Chlebowski, Garcia, G. R., La Du, J. K., Bisson, W. H., Truong, L., SL, M. Simonich, and Tanguay, R. L., “Mechanistic investigations into the developmental toxicity of nitrated and heterocyclic PAHs.”, Toxicol Sci, 2017.

H. Kim, Banerjee, N., Ivanov, I., Pfent, C. M., Prudhomme, K. R., Bisson, W. H., Dashwood, R. H., Talcott, S. T., and Mertens-Talcott, S. U., “Comparison of anti-inflammatory mechanisms of mango ( Mangifera Indica L.) and pomegranate ( Punica Granatum L.) in a preclinical model of colitis”, Molecular Nutrition & Food Research, p. n/a - n/a, 2016.

L. Yang, Broderick, D., Campbell, Y., Gombart, A. F., Stevens, J. F., Jiang, Y., Hsu, V. L., Bisson, W. H., and Maier, C. S., “Conformational Modulation of the Farnesoid X Receptor by Prenylflavonoids: Insights from Hydrogen Deuterium Exchange Mass Spectrometry (HDX-MS), Fluorescence Titration and Molecular Docking Studies.”, Biochim Biophys Acta, 2016.

T. D. Hubbard, Murray, I. A., Bisson, W. H., Sullivan, A. P., Sebastian, A., Perry, G. H., Jablonski, N. G., and Perdew, G. H., “Divergent Ah receptor ligand selectivity during hominin evolution.”, Mol Biol Evol, 2016.

E. Kim, Bisson, W. H., Löhr, C. V., Williams, D. E., Ho, E., Dashwood, R. H., and Rajendran, P., “Histone and Non-Histone Targets of Dietary Deacetylase Inhibitors.”, Curr Top Med Chem, vol. 16, no. 7, pp. 714-31, 2016.

M. J. Nemec, Kim, H., Marciante, A. B., Barnes, R. C., Hendrick, E. D., Bisson, W. H., Talcott, S. T., and Mertens-Talcott, S. U., “Polyphenolics from mango (Mangifera indica L.) suppress breast cancer ductal carcinoma in situ proliferation through activation of AMPK pathway and suppression of mTOR in athymic nude mice.”, J Nutr Biochem, vol. 41, pp. 12-19, 2016.

T. D. Hubbard, Murray, I. A., Bisson, W. H., Lahoti, T. S., Gowda, K., Amin, S. G., Patterson, A. D., and Perdew, G. H., “Adaptation of the human aryl hydrocarbon receptor to sense microbiota-derived indoles”, Scientific reports, vol. 5, 2015.

D. C. Koch, Jang, H. S., O'Donnell, E. F., Punj, S., Kopparapu, P. R., Bisson, W. H., Kerkvliet, N. I., and Kolluri, S., “Anti-androgen flutamide suppresses hepatocellular carcinoma cell proliferation via the aryl hydrocarbon receptor mediated induction of transforming growth factor-β1.”, Oncogene, 2015.

Z. Hu, Brooks, S. A., Dormoy, V., Hsu, C. - W., Hsu, H. - Y., Lin, L. - T., Massfelder, T., W Rathmell, K., Xia, M., Al-Mulla, F., and Bisson, W. H., “Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: focus on the cancer hallmark of tumor angiogenesis”, Carcinogenesis, vol. 36, pp. S184–S202, 2015.

W. H. Goodson, Lowe, L., Carpenter, D. O., Gilbertson, M., Ali, A. Manaf, Salsamendi, A. Lopez de C., Lasfar, A., Carnero, A., Azqueta, A., Amedei, A., and Bisson, W. H., “Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead”, Carcinogenesis, vol. 36, pp. S254–S296, 2015.

S. A. S. Langie, Koppen, G., Desaulniers, D., Al-Mulla, F., Al-Temaimi, R., Amedei, A., Azqueta, A., Bisson, W. H., Brown, D., Brunborg, G., and , “Causes of genome instability: the effect of low dose chemical exposures in modern society”, Carcinogenesis, vol. 36, pp. S61–S88, 2015.

J. Kravchenko, Corsini, E., Williams, M. A., Decker, W., Manjili, M. H., Otsuki, T., Singh, N., Al-Mulla, F., Al-Temaimi, R., Amedei, A., and Bisson, W. H., “Chemical compounds from anthropogenic environment and immune evasion mechanisms: potential interactions”, Carcinogenesis, p. bgv033, 2015.