Sponsor: 
Corteva Ag Sci
Award Ceiling: 
50000
Posted Date: 
October 20, 2021
Due Date: Full Proposal: 
November 30, 2021
We are seeking short, non-confidential proposals that describe a plan to demonstrate the transfer of and expression from large fungal biosynthetic gene clusters in a heterologous fungal (yeast or filamentous fungi) host, leading to detectable production of natural products. Must haves: A heterologous fungal (yeast or filamentous fungi) expression system capable of producing natural products from various classes: e.g., non-ribosomal peptide, polyketide, terpenoids, etc. Demonstrated success in the transfer of and expression from fungal biosynthetic gene clusters comprised of >5 genes to a heterologous fungal host system Demonstrated success in the heterologous production of a natural product from at least one class Openness to jointly identify target GBCs with Corteva scientists, if your proposal is selected